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HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase

BACKGROUND: Human Cytomegalovirus (HCMV) has been implicated in the acceleration of vascular disease and chronic allograft rejection. Recently, the virus has been associated with glioblastoma and other tumors. We have previously shown that the HCMV-encoded chemokine receptor pUS28 mediates smooth mu...

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Detalles Bibliográficos
Autores principales: Vomaske, Jennifer, Varnum, Susan, Melnychuk, Ryan, Smith, Patricia, Pasa-Tolic, Ljiljana, Shutthanandan, Janani I, Streblow, Daniel N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050435/
https://www.ncbi.nlm.nih.gov/pubmed/21429240
http://dx.doi.org/10.1186/2042-4280-1-2