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Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines

BACKGROUND: Paclitaxel is a microtubule-stabilizing drug that has been commonly used in treating cancer. Due to genetic heterogeneity within patient populations, therapeutic response rates often vary. Here we used the NCI60 panel to identify SNPs associated with paclitaxel sensitivity. Using the pan...

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Detalles Bibliográficos
Autores principales:	Eng, Lawson, Ibrahim-zada, Irada, Jarjanazi, Hamdi, Savas, Sevtap, Meschian, Mehran, Pritchard, Kathleen I, Ozcelik, Hilmi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050680/ https://www.ncbi.nlm.nih.gov/pubmed/21314952 http://dx.doi.org/10.1186/1755-8794-4-18

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