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Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

BACKGROUND: Alpha-1 antitrypsin (AAT) is a multi-functional protein that has anti-inflammatory and tissue protective properties. We previously reported that human AAT (hAAT) gene therapy prevented autoimmune diabetes in non-obese diabetic (NOD) mice and suppressed arthritis development in combinatio...

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Detalles Bibliográficos
Autores principales:	Grimstein, Christian, Choi, Young-Kook, Wasserfall, Clive H, Satoh, Minoru, Atkinson, Mark A, Brantly, Mark L, Campbell-Thompson, Martha, Song, Sihong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050720/ https://www.ncbi.nlm.nih.gov/pubmed/21345239 http://dx.doi.org/10.1186/1479-5876-9-21

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