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Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas

BACKGROUND: The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo. However, current prediction methods generally rely on statistical models that imperfectly model transcription factor binding. Generation of ne...

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Detalles Bibliográficos
Autores principales: Hill, Jonathon T, Anderson, Keith R, Mastracci, Teresa L, Kaestner, Klaus H, Sussel, Lori
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050729/
https://www.ncbi.nlm.nih.gov/pubmed/21352540
http://dx.doi.org/10.1186/1471-2105-12-62