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Predicting the points of interaction of small molecules in the NF-κB pathway

BACKGROUND: The similarity property principle has been used extensively in drug discovery to identify small compounds that interact with specific drug targets. Here we show it can be applied to identify the interactions of small molecules within the NF-κB signalling pathway. RESULTS: Clusters that c...

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Detalles Bibliográficos
Autores principales:	Patel, Yogendra, Heyward, Catherine A, White, Michael RH, Kell, Douglas B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050742/ https://www.ncbi.nlm.nih.gov/pubmed/21342508 http://dx.doi.org/10.1186/1752-0509-5-32

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