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mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway

BACKGROUND: In order to understand the interaction between the metabotropic glutamate subtype 5 (mGluR5) and N-methyl-D-aspartate (NMDA) receptors, the influence of mGluR5 positive modulators in the inhibition of NMDA receptors by the noncompetitive antagonist ketamine, the competitive antagonist D-...

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Detalles Bibliográficos
Autores principales: Chen, Hwei-Hsien, Liao, Pei-Fei, Chan, Ming-Huan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050796/
https://www.ncbi.nlm.nih.gov/pubmed/21342491
http://dx.doi.org/10.1186/1423-0127-18-19

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