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Functional Role of Glutamine 28 and Arginine 39 in Double Stranded RNA Cleavage by Human Pancreatic Ribonuclease

Human pancreatic ribonuclease (HPR), a member of RNase A superfamily, has a high activity on double stranded (ds) RNA. By virtue of this activity HPR appears to be involved in the host-defense against pathogenic viruses. To delineate the mechanism of dsRNA cleavage by HPR, we have investigated the r...

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Detalles Bibliográficos
Autores principales:	Rehman, Md. Tabish, Dey, Punyatirtha, Hassan, Md. Imtaiyaz, Ahmad, Faizan, Batra, Janendra K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050822/ https://www.ncbi.nlm.nih.gov/pubmed/21408145 http://dx.doi.org/10.1371/journal.pone.0017159

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