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HAMLET Binding to α-Actinin Facilitates Tumor Cell Detachment
Cell adhesion is tightly regulated by specific molecular interactions and detachment from the extracellular matrix modifies proliferation and survival. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a protein-lipid complex with tumoricidal activity that also triggers tumor cell detac...
Autores principales: | Trulsson, Maria, Yu, Hao, Gisselsson, Lennart, Chao, Yinxia, Urbano, Alexander, Aits, Sonja, Mossberg, Ann-Kristin, Svanborg, Catharina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050841/ https://www.ncbi.nlm.nih.gov/pubmed/21408150 http://dx.doi.org/10.1371/journal.pone.0017179 |
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