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A Novel Extracellular Hsp90 Mediated Co-Receptor Function for LRP1 Regulates EphA2 Dependent Glioblastoma Cell Invasion

BACKGROUND: Extracellular Hsp90 protein (eHsp90) potentiates cancer cell motility and invasion through a poorly understood mechanism involving ligand mediated function with its cognate receptor LRP1. Glioblastoma multiforme (GBM) represents one of the most aggressive and lethal brain cancers. The re...

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Detalles Bibliográficos
Autores principales:	Gopal, Udhayakumar, Bohonowych, Jessica E., Lema-Tome, Carla, Liu, Angen, Garrett-Mayer, Elizabeth, Wang, Bingcheng, Isaacs, Jennifer S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050925/ https://www.ncbi.nlm.nih.gov/pubmed/21408136 http://dx.doi.org/10.1371/journal.pone.0017649

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