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LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES

BACKGROUND: Cutaneous leiomyomas are benign smooth muscle tumors that comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma. AIM: The objective of this study was to report a series of cases seen in last 8 years in a tertiary care hospital in north India and to dis...

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Autores principales: Malhotra, Purnima, Walia, Harpreet, Singh, Avninder, Ramesh, V
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051292/
https://www.ncbi.nlm.nih.gov/pubmed/21430885
http://dx.doi.org/10.4103/0019-5154.74535
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author Malhotra, Purnima
Walia, Harpreet
Singh, Avninder
Ramesh, V
author_facet Malhotra, Purnima
Walia, Harpreet
Singh, Avninder
Ramesh, V
author_sort Malhotra, Purnima
collection PubMed
description BACKGROUND: Cutaneous leiomyomas are benign smooth muscle tumors that comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma. AIM: The objective of this study was to report a series of cases seen in last 8 years in a tertiary care hospital in north India and to discuss their clinicopathologic findings. MATERIAL AND METHODS: Paraffin-embedded blocks of cases reported as cutaneous leiomyoma from 1999 to 2007 were retrieved from the Institute of Pathology, New Delhi, and their clinical parameters were noted. Their histopathological features were reviewed on hematoxylin-eosin stained slides. Immunohistochemistry was performed where necessary. RESULTS: Twenty-seven cases of piloleiomyoma, three cases of angioleiomyoma, five breast leiomyomas, and two scrotal leiomyomas were seen in patients ranging from 21 to 65 years of age, with an average of 38.2 years at presentation. There was a male predominance with 26 males and 11 females (M:F = 2.2:1). Solitary lesions (n = 21) were more common than multiple ( n = 16). The trunk and upper limbs were involved most commonly, comprising 23 of 37 (62.2%) cases. This was followed by lower limb, face, breast, and scrotum. CONCLUSION: Cutaneous leiomyomas are rare lesions and form an important clinical differential diagnosis of painful papulonodules. These must be biopsied in order to differentiate them from other spindle cell lesions.
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spelling pubmed-30512922011-03-22 LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES Malhotra, Purnima Walia, Harpreet Singh, Avninder Ramesh, V Indian J Dermatol Original Article BACKGROUND: Cutaneous leiomyomas are benign smooth muscle tumors that comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma. AIM: The objective of this study was to report a series of cases seen in last 8 years in a tertiary care hospital in north India and to discuss their clinicopathologic findings. MATERIAL AND METHODS: Paraffin-embedded blocks of cases reported as cutaneous leiomyoma from 1999 to 2007 were retrieved from the Institute of Pathology, New Delhi, and their clinical parameters were noted. Their histopathological features were reviewed on hematoxylin-eosin stained slides. Immunohistochemistry was performed where necessary. RESULTS: Twenty-seven cases of piloleiomyoma, three cases of angioleiomyoma, five breast leiomyomas, and two scrotal leiomyomas were seen in patients ranging from 21 to 65 years of age, with an average of 38.2 years at presentation. There was a male predominance with 26 males and 11 females (M:F = 2.2:1). Solitary lesions (n = 21) were more common than multiple ( n = 16). The trunk and upper limbs were involved most commonly, comprising 23 of 37 (62.2%) cases. This was followed by lower limb, face, breast, and scrotum. CONCLUSION: Cutaneous leiomyomas are rare lesions and form an important clinical differential diagnosis of painful papulonodules. These must be biopsied in order to differentiate them from other spindle cell lesions. Medknow Publications & Media Pvt Ltd 2010 /pmc/articles/PMC3051292/ /pubmed/21430885 http://dx.doi.org/10.4103/0019-5154.74535 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Malhotra, Purnima
Walia, Harpreet
Singh, Avninder
Ramesh, V
LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title_full LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title_fullStr LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title_full_unstemmed LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title_short LEIOMYOMA CUTIS: A CLINICOPATHOLOGICAL SERIES OF 37 CASES
title_sort leiomyoma cutis: a clinicopathological series of 37 cases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051292/
https://www.ncbi.nlm.nih.gov/pubmed/21430885
http://dx.doi.org/10.4103/0019-5154.74535
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AT singhavninder leiomyomacutisaclinicopathologicalseriesof37cases
AT rameshv leiomyomacutisaclinicopathologicalseriesof37cases