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4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine
In the title compound, C(22)H(19)Cl(2)N(5)S, the thiazole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°. In the crystal, intermolecular N—H⋯N hydrogen bonds link pairs of molecules into centrosymmetric dimers..
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051541/ https://www.ncbi.nlm.nih.gov/pubmed/21522953 http://dx.doi.org/10.1107/S1600536810053547 |
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author | Li, Hai-Bo Shi, Hai-Bo Hu, Wei-Xiao |
author_facet | Li, Hai-Bo Shi, Hai-Bo Hu, Wei-Xiao |
author_sort | Li, Hai-Bo |
collection | PubMed |
description | In the title compound, C(22)H(19)Cl(2)N(5)S, the thiazole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°. In the crystal, intermolecular N—H⋯N hydrogen bonds link pairs of molecules into centrosymmetric dimers.. |
format | Text |
id | pubmed-3051541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30515412011-04-26 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine Li, Hai-Bo Shi, Hai-Bo Hu, Wei-Xiao Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(19)Cl(2)N(5)S, the thiazole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°. In the crystal, intermolecular N—H⋯N hydrogen bonds link pairs of molecules into centrosymmetric dimers.. International Union of Crystallography 2011-01-08 /pmc/articles/PMC3051541/ /pubmed/21522953 http://dx.doi.org/10.1107/S1600536810053547 Text en © Li et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Li, Hai-Bo Shi, Hai-Bo Hu, Wei-Xiao 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title | 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title_full | 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title_fullStr | 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title_full_unstemmed | 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title_short | 4-{2-[(3,4-Dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine |
title_sort | 4-{2-[(3,4-dichlorophenyl)(methyl)amino]-4-methyl-1,3-thiazol-5-yl}-n-(3-methylphenyl)pyrimidin-2-amine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051541/ https://www.ncbi.nlm.nih.gov/pubmed/21522953 http://dx.doi.org/10.1107/S1600536810053547 |
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