rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data

The crystal structure of the title water-soluble analogue of vitamin E, trolox amide, C(14)H(19)NO(3), solved and refined against synchrotron diffraction data, contains two mol­ecules in the asymmetric unit. In both molecules, the heterocyclic ring is in a half-chair conformation. The crystal packin...

Descripción completa

Detalles Bibliográficos
Autores principales: Brzezinski, Krzysztof, Dauter, Zbigniew, Baj, Aneta, Wałejko, Piotr, Witkowski, Stanisław
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051603/
https://www.ncbi.nlm.nih.gov/pubmed/21523156
http://dx.doi.org/10.1107/S1600536811002807
_version_ 1782199518244110336
author Brzezinski, Krzysztof
Dauter, Zbigniew
Baj, Aneta
Wałejko, Piotr
Witkowski, Stanisław
author_facet Brzezinski, Krzysztof
Dauter, Zbigniew
Baj, Aneta
Wałejko, Piotr
Witkowski, Stanisław
author_sort Brzezinski, Krzysztof
collection PubMed
description The crystal structure of the title water-soluble analogue of vitamin E, trolox amide, C(14)H(19)NO(3), solved and refined against synchrotron diffraction data, contains two mol­ecules in the asymmetric unit. In both molecules, the heterocyclic ring is in a half-chair conformation. The crystal packing features a herring-bone pattern generated by N—H⋯O hydrogen bonds between the hy­droxy and amide groups. O—H⋯O hydrogen bonds also occur.
format Text
id pubmed-3051603
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-30516032011-04-26 rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data Brzezinski, Krzysztof Dauter, Zbigniew Baj, Aneta Wałejko, Piotr Witkowski, Stanisław Acta Crystallogr Sect E Struct Rep Online Organic Papers The crystal structure of the title water-soluble analogue of vitamin E, trolox amide, C(14)H(19)NO(3), solved and refined against synchrotron diffraction data, contains two mol­ecules in the asymmetric unit. In both molecules, the heterocyclic ring is in a half-chair conformation. The crystal packing features a herring-bone pattern generated by N—H⋯O hydrogen bonds between the hy­droxy and amide groups. O—H⋯O hydrogen bonds also occur. International Union of Crystallography 2011-01-29 /pmc/articles/PMC3051603/ /pubmed/21523156 http://dx.doi.org/10.1107/S1600536811002807 Text en © Brzezinski et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Brzezinski, Krzysztof
Dauter, Zbigniew
Baj, Aneta
Wałejko, Piotr
Witkowski, Stanisław
rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title_full rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title_fullStr rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title_full_unstemmed rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title_short rac-6-Hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
title_sort rac-6-hy­droxy-2,5,7,8-tetra­methyl­chroman-2-carboxamide from synchrotron data
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051603/
https://www.ncbi.nlm.nih.gov/pubmed/21523156
http://dx.doi.org/10.1107/S1600536811002807
work_keys_str_mv AT brzezinskikrzysztof rac6hydroxy2578tetramethylchroman2carboxamidefromsynchrotrondata
AT dauterzbigniew rac6hydroxy2578tetramethylchroman2carboxamidefromsynchrotrondata
AT bajaneta rac6hydroxy2578tetramethylchroman2carboxamidefromsynchrotrondata
AT wałejkopiotr rac6hydroxy2578tetramethylchroman2carboxamidefromsynchrotrondata
AT witkowskistanisław rac6hydroxy2578tetramethylchroman2carboxamidefromsynchrotrondata

Ejemplares similares