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6-Cyclohexylmethyl-5-ethyl-2-[(2-oxo-2-phenylethyl)sulfanyl]pyrimidin-4(3H)-one
In the title compound, C(21)H(26)N(2)O(2)S, the cyclohexane ring adopts a chair conformation. The angle at the methylene bridge linking the pyrimidine and cyclohexane rings is 113.41 (13)°. This is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051611/ https://www.ncbi.nlm.nih.gov/pubmed/21523182 http://dx.doi.org/10.1107/S1600536811003175 |