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5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol
In the crystal structure of the title compound, C(7)H(6)BFO(2), a broad-spectrum antifungal drug (AN2690), the planar [maximum deviation 0.035 (1) Å] molecules form centrosymmetric R (2) (2)(8) dimers via strong O—H⋯O hydrogen bonds. The dimers are arranged into layers by weak intermolecular C—H⋯...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051614/ https://www.ncbi.nlm.nih.gov/pubmed/21523085 http://dx.doi.org/10.1107/S1600536811001632 |
Sumario: | In the crystal structure of the title compound, C(7)H(6)BFO(2), a broad-spectrum antifungal drug (AN2690), the planar [maximum deviation 0.035 (1) Å] molecules form centrosymmetric R (2) (2)(8) dimers via strong O—H⋯O hydrogen bonds. The dimers are arranged into layers by weak intermolecular C—H⋯O and C—H⋯F hydrogen bonds. The symmetry of this two-dimensional supramolecular assembly can be described by the layer group p [Image: see text] and topologically classified as a simple uninodal four-connected two-dimensional network of a (4.4.4.4.6.6) topology. Further weak C—H⋯O interactions build up the three-dimensional structure. |
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