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1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone
In the title compound, C(17)H(17)Cl(2)NO(2), the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations with respect to the adjacent C=C bond...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051630/ https://www.ncbi.nlm.nih.gov/pubmed/21523057 http://dx.doi.org/10.1107/S1600536810052839 |
Sumario: | In the title compound, C(17)H(17)Cl(2)NO(2), the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations with respect to the adjacent C=C bonds in the dihydropyridine ring. The 2,4-dichlorophenyl ring is almost planar [r.m.s. deviation = 0.0045 (1) Å] and almost perpendicular [89.27 (3)°] to the mean plane of the dihydropyridine ring. In the crystal, an N—H⋯O hydrogen bond links molecules into a zigzag chain along the ac diagonal. C—H⋯Cl contacts form centrosymmetric dimers and additional weak C—H⋯O contacts further consolidate the packing. |
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