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1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone
In the title compound, C(17)H(17)Cl(2)NO(2), the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations with respect to the adjacent C=C bond...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051630/ https://www.ncbi.nlm.nih.gov/pubmed/21523057 http://dx.doi.org/10.1107/S1600536810052839 |
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author | Sundar, J. Kalyana Reddy, B. Palakshi Vijayakumar, V. Natarajan, S. Suresh, J. Lakshman, P. L. Nilantha |
author_facet | Sundar, J. Kalyana Reddy, B. Palakshi Vijayakumar, V. Natarajan, S. Suresh, J. Lakshman, P. L. Nilantha |
author_sort | Sundar, J. Kalyana |
collection | PubMed |
description | In the title compound, C(17)H(17)Cl(2)NO(2), the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations with respect to the adjacent C=C bonds in the dihydropyridine ring. The 2,4-dichlorophenyl ring is almost planar [r.m.s. deviation = 0.0045 (1) Å] and almost perpendicular [89.27 (3)°] to the mean plane of the dihydropyridine ring. In the crystal, an N—H⋯O hydrogen bond links molecules into a zigzag chain along the ac diagonal. C—H⋯Cl contacts form centrosymmetric dimers and additional weak C—H⋯O contacts further consolidate the packing. |
format | Text |
id | pubmed-3051630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30516302011-04-26 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone Sundar, J. Kalyana Reddy, B. Palakshi Vijayakumar, V. Natarajan, S. Suresh, J. Lakshman, P. L. Nilantha Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(17)H(17)Cl(2)NO(2), the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations with respect to the adjacent C=C bonds in the dihydropyridine ring. The 2,4-dichlorophenyl ring is almost planar [r.m.s. deviation = 0.0045 (1) Å] and almost perpendicular [89.27 (3)°] to the mean plane of the dihydropyridine ring. In the crystal, an N—H⋯O hydrogen bond links molecules into a zigzag chain along the ac diagonal. C—H⋯Cl contacts form centrosymmetric dimers and additional weak C—H⋯O contacts further consolidate the packing. International Union of Crystallography 2011-01-15 /pmc/articles/PMC3051630/ /pubmed/21523057 http://dx.doi.org/10.1107/S1600536810052839 Text en © Sundar et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Sundar, J. Kalyana Reddy, B. Palakshi Vijayakumar, V. Natarajan, S. Suresh, J. Lakshman, P. L. Nilantha 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title | 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title_full | 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title_fullStr | 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title_full_unstemmed | 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title_short | 1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
title_sort | 1,1′-[4-(2,4-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051630/ https://www.ncbi.nlm.nih.gov/pubmed/21523057 http://dx.doi.org/10.1107/S1600536810052839 |
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