rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate

The title mol­ecule, C(21)H(30)N(2)O(5), is chiral with four stereogenic centres. The crystal is a racemate and consists of enanti­omeric pairs with the relative configuration rac-(6S*,7R*,8R*,9S*). The ethyl fragment of the eth­oxy­carbonyl group at position 6 is disordered in a 0.46 (3):0.54 (3) r...

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Detalles Bibliográficos
Autores principales: Maharramov, Abel M., Ismiyev, Arif I., Rashidov, Bahruz A., Rahimova, Gunel M., Allahverdiyev, Mirza A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051672/
https://www.ncbi.nlm.nih.gov/pubmed/21522983
http://dx.doi.org/10.1107/S1600536810054498
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author Maharramov, Abel M.
Ismiyev, Arif I.
Rashidov, Bahruz A.
Rahimova, Gunel M.
Allahverdiyev, Mirza A.
author_facet Maharramov, Abel M.
Ismiyev, Arif I.
Rashidov, Bahruz A.
Rahimova, Gunel M.
Allahverdiyev, Mirza A.
author_sort Maharramov, Abel M.
collection PubMed
description The title mol­ecule, C(21)H(30)N(2)O(5), is chiral with four stereogenic centres. The crystal is a racemate and consists of enanti­omeric pairs with the relative configuration rac-(6S*,7R*,8R*,9S*). The ethyl fragment of the eth­oxy­carbonyl group at position 6 is disordered in a 0.46 (3):0.54 (3) ratio. The crystal structure features inter­molecular N—H⋯O. Intra­molecular O—H⋯N and N—H⋯O hydrogen bonds also occur.
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spelling pubmed-30516722011-04-26 rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate Maharramov, Abel M. Ismiyev, Arif I. Rashidov, Bahruz A. Rahimova, Gunel M. Allahverdiyev, Mirza A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title mol­ecule, C(21)H(30)N(2)O(5), is chiral with four stereogenic centres. The crystal is a racemate and consists of enanti­omeric pairs with the relative configuration rac-(6S*,7R*,8R*,9S*). The ethyl fragment of the eth­oxy­carbonyl group at position 6 is disordered in a 0.46 (3):0.54 (3) ratio. The crystal structure features inter­molecular N—H⋯O. Intra­molecular O—H⋯N and N—H⋯O hydrogen bonds also occur. International Union of Crystallography 2011-01-08 /pmc/articles/PMC3051672/ /pubmed/21522983 http://dx.doi.org/10.1107/S1600536810054498 Text en © Maharramov et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Maharramov, Abel M.
Ismiyev, Arif I.
Rashidov, Bahruz A.
Rahimova, Gunel M.
Allahverdiyev, Mirza A.
rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title_full rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title_fullStr rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title_full_unstemmed rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title_short rac-Diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
title_sort rac-diethyl 9-hy­droxy-9-methyl-7-phenyl-1,4-diaza­spiro­[4.5]decane-6,8-dicarboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051672/
https://www.ncbi.nlm.nih.gov/pubmed/21522983
http://dx.doi.org/10.1107/S1600536810054498
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