(3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one

The β-lactam ring of the title compound, C(26)H(25)ClN(2)O(4), is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ri...

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Detalles Bibliográficos
Autores principales: Akkurt, Mehmet, Jarrahpour, Aliasghar, Sharghi, Hashem, Badrabady, Seid Ali Torabi, Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051698/
https://www.ncbi.nlm.nih.gov/pubmed/21523011
http://dx.doi.org/10.1107/S1600536811000675
Descripción
Sumario:The β-lactam ring of the title compound, C(26)H(25)ClN(2)O(4), is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ring, respectively. The conformation of the title compound is stabilized by intra­molecular C—H⋯O and O—H⋯N inter­actions. The crystal structure features C—H⋯π and aromatic π–π stacking inter­actions [centroid–centroid distances = 3.684 (4) and 3.883 (4) Å].

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