(3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one

The β-lactam ring of the title compound, C(26)H(25)ClN(2)O(4), is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ri...

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Autores principales: Akkurt, Mehmet, Jarrahpour, Aliasghar, Sharghi, Hashem, Badrabady, Seid Ali Torabi, Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051698/
https://www.ncbi.nlm.nih.gov/pubmed/21523011
http://dx.doi.org/10.1107/S1600536811000675
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author Akkurt, Mehmet
Jarrahpour, Aliasghar
Sharghi, Hashem
Badrabady, Seid Ali Torabi
Büyükgüngör, Orhan
author_facet Akkurt, Mehmet
Jarrahpour, Aliasghar
Sharghi, Hashem
Badrabady, Seid Ali Torabi
Büyükgüngör, Orhan
author_sort Akkurt, Mehmet
collection PubMed
description The β-lactam ring of the title compound, C(26)H(25)ClN(2)O(4), is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ring, respectively. The conformation of the title compound is stabilized by intra­molecular C—H⋯O and O—H⋯N inter­actions. The crystal structure features C—H⋯π and aromatic π–π stacking inter­actions [centroid–centroid distances = 3.684 (4) and 3.883 (4) Å].
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spelling pubmed-30516982011-04-26 (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one Akkurt, Mehmet Jarrahpour, Aliasghar Sharghi, Hashem Badrabady, Seid Ali Torabi Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers The β-lactam ring of the title compound, C(26)H(25)ClN(2)O(4), is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ring, respectively. The conformation of the title compound is stabilized by intra­molecular C—H⋯O and O—H⋯N inter­actions. The crystal structure features C—H⋯π and aromatic π–π stacking inter­actions [centroid–centroid distances = 3.684 (4) and 3.883 (4) Å]. International Union of Crystallography 2011-01-12 /pmc/articles/PMC3051698/ /pubmed/21523011 http://dx.doi.org/10.1107/S1600536811000675 Text en © Akkurt et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Akkurt, Mehmet
Jarrahpour, Aliasghar
Sharghi, Hashem
Badrabady, Seid Ali Torabi
Büyükgüngör, Orhan
(3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title_full (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title_fullStr (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title_full_unstemmed (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title_short (3R*,4R*)-1-(4-Chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
title_sort (3r*,4r*)-1-(4-chloro­phen­yl)-4-[2-hy­droxy-3-(morpholinomethyl)­phen­yl]-3-phen­oxy­azetidin-2-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051698/
https://www.ncbi.nlm.nih.gov/pubmed/21523011
http://dx.doi.org/10.1107/S1600536811000675
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