N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine

The asymmetric unit of the title compound, C(23)H(23)N(5)OS, contains two independent mol­ecules. In one mol­ecule, the thia­zole and pyrimidine rings are almost co-planar, making a dihedral angle of 2.48 (8)°. In the other mol­ecule, the corresponding dihedral angle is 12.82 (8)°. The crystal struc...

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Detalles Bibliográficos
Autores principales: Shi, Hai-Bo, Li, Hai-Bo, Hu, Wei-Xiao
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051738/
https://www.ncbi.nlm.nih.gov/pubmed/21522954
http://dx.doi.org/10.1107/S1600536810053559
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author Shi, Hai-Bo
Li, Hai-Bo
Hu, Wei-Xiao
author_facet Shi, Hai-Bo
Li, Hai-Bo
Hu, Wei-Xiao
author_sort Shi, Hai-Bo
collection PubMed
description The asymmetric unit of the title compound, C(23)H(23)N(5)OS, contains two independent mol­ecules. In one mol­ecule, the thia­zole and pyrimidine rings are almost co-planar, making a dihedral angle of 2.48 (8)°. In the other mol­ecule, the corresponding dihedral angle is 12.82 (8)°. The crystal structure is stabilized by weak inter­molecular N—H⋯N and C—H⋯O inter­actions that extend along the b axis.
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spelling pubmed-30517382011-04-26 N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine Shi, Hai-Bo Li, Hai-Bo Hu, Wei-Xiao Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(23)H(23)N(5)OS, contains two independent mol­ecules. In one mol­ecule, the thia­zole and pyrimidine rings are almost co-planar, making a dihedral angle of 2.48 (8)°. In the other mol­ecule, the corresponding dihedral angle is 12.82 (8)°. The crystal structure is stabilized by weak inter­molecular N—H⋯N and C—H⋯O inter­actions that extend along the b axis. International Union of Crystallography 2011-01-08 /pmc/articles/PMC3051738/ /pubmed/21522954 http://dx.doi.org/10.1107/S1600536810053559 Text en © Shi et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Shi, Hai-Bo
Li, Hai-Bo
Hu, Wei-Xiao
N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title_full N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title_fullStr N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title_full_unstemmed N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title_short N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
title_sort n-(3-meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051738/
https://www.ncbi.nlm.nih.gov/pubmed/21522954
http://dx.doi.org/10.1107/S1600536810053559
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AT huweixiao n3methoxyphenyl44methyl2methyl4methylphenylamino13thiazol5ylpyrimidin2amine

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