1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one

The title compound, (I) C(28)H(24)N(4)O(4), is the trans diastereo­isomer of the compound 1-[2-(4-nitro­phen­yl)-6-(5-phenyl-3-isoxazol­yl)-1,2,3,4-tetra­hydro-4-quinolin­yl]-2-pyrrolidinone monohydrate, (II) [Gutierrez et al. (2011 ▶). Acta Cryst. E67, o175–o176]. The most obvious differences betwe...

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Autores principales: Gutierrez, Margarita, Astudillo, Luis, Quesada, Luisa, Brito, Iván, López-Rodríguez, Matías
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051757/
https://www.ncbi.nlm.nih.gov/pubmed/21522997
http://dx.doi.org/10.1107/S1600536810054048
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author Gutierrez, Margarita
Astudillo, Luis
Quesada, Luisa
Brito, Iván
López-Rodríguez, Matías
author_facet Gutierrez, Margarita
Astudillo, Luis
Quesada, Luisa
Brito, Iván
López-Rodríguez, Matías
author_sort Gutierrez, Margarita
collection PubMed
description The title compound, (I) C(28)H(24)N(4)O(4), is the trans diastereo­isomer of the compound 1-[2-(4-nitro­phen­yl)-6-(5-phenyl-3-isoxazol­yl)-1,2,3,4-tetra­hydro-4-quinolin­yl]-2-pyrrolidinone monohydrate, (II) [Gutierrez et al. (2011 ▶). Acta Cryst. E67, o175–o176]. The most obvious differences between the diastereo­isomers are the dihedral angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2); 56.4 (2) and 33.3 (2); 11.0 (2)°, respectively, for (II) 75.4 (2) and 5.8 (3), respectively, for (I)]. In the crystal of (I), the mol­ecules are linked by N—H⋯O inter­actions into a chain along [001] with graph-set notation C(8).
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spelling pubmed-30517572011-04-26 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one Gutierrez, Margarita Astudillo, Luis Quesada, Luisa Brito, Iván López-Rodríguez, Matías Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, (I) C(28)H(24)N(4)O(4), is the trans diastereo­isomer of the compound 1-[2-(4-nitro­phen­yl)-6-(5-phenyl-3-isoxazol­yl)-1,2,3,4-tetra­hydro-4-quinolin­yl]-2-pyrrolidinone monohydrate, (II) [Gutierrez et al. (2011 ▶). Acta Cryst. E67, o175–o176]. The most obvious differences between the diastereo­isomers are the dihedral angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2); 56.4 (2) and 33.3 (2); 11.0 (2)°, respectively, for (II) 75.4 (2) and 5.8 (3), respectively, for (I)]. In the crystal of (I), the mol­ecules are linked by N—H⋯O inter­actions into a chain along [001] with graph-set notation C(8). International Union of Crystallography 2011-01-08 /pmc/articles/PMC3051757/ /pubmed/21522997 http://dx.doi.org/10.1107/S1600536810054048 Text en © Gutierrez et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Gutierrez, Margarita
Astudillo, Luis
Quesada, Luisa
Brito, Iván
López-Rodríguez, Matías
1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title_full 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title_fullStr 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title_full_unstemmed 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title_short 1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
title_sort 1-[2-(4-nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051757/
https://www.ncbi.nlm.nih.gov/pubmed/21522997
http://dx.doi.org/10.1107/S1600536810054048
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