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2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole
In the title compound, C(22)H(23)FN(2)OS, the piperidine ring shows chair confirmation and the two benzene rings make a dihedral angle of 17.0 (6)°. The thiazole fragment is essentially planar with an r.m.s. deviation of 0.004 (2) Å and a maximum deviation of 0.006 (2) Å.. In the crystal, intermol...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051797/ https://www.ncbi.nlm.nih.gov/pubmed/21523040 http://dx.doi.org/10.1107/S1600536810054103 |
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author | Guo, Chang-Bin Lv, Chao Wei, Wei Zhou, Hua |
author_facet | Guo, Chang-Bin Lv, Chao Wei, Wei Zhou, Hua |
author_sort | Guo, Chang-Bin |
collection | PubMed |
description | In the title compound, C(22)H(23)FN(2)OS, the piperidine ring shows chair confirmation and the two benzene rings make a dihedral angle of 17.0 (6)°. The thiazole fragment is essentially planar with an r.m.s. deviation of 0.004 (2) Å and a maximum deviation of 0.006 (2) Å.. In the crystal, intermolecular C—H⋯π interactions lead to the formation of a layer structure. |
format | Text |
id | pubmed-3051797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30517972011-04-26 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole Guo, Chang-Bin Lv, Chao Wei, Wei Zhou, Hua Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(23)FN(2)OS, the piperidine ring shows chair confirmation and the two benzene rings make a dihedral angle of 17.0 (6)°. The thiazole fragment is essentially planar with an r.m.s. deviation of 0.004 (2) Å and a maximum deviation of 0.006 (2) Å.. In the crystal, intermolecular C—H⋯π interactions lead to the formation of a layer structure. International Union of Crystallography 2011-01-12 /pmc/articles/PMC3051797/ /pubmed/21523040 http://dx.doi.org/10.1107/S1600536810054103 Text en © Guo et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Guo, Chang-Bin Lv, Chao Wei, Wei Zhou, Hua 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title | 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title_full | 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title_fullStr | 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title_full_unstemmed | 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title_short | 2-(4-Fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
title_sort | 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-5-(piperidin-1-ylmethyl)thiazole |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051797/ https://www.ncbi.nlm.nih.gov/pubmed/21523040 http://dx.doi.org/10.1107/S1600536810054103 |
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