(1S,2S,3R,4S,5R,7S,8S,10R,13S)-2-Debenzoyl-10-deacetyl-2-(3-fluoro­benzo­yl)-7,10-bis­(2,2,2-trichloro­eth­oxy­carbon­yl)baccatin III ethyl acetate monosolvate monohydrate

In the title compound, C(35)H(37)Cl(6)FO(14)·C(4)H(8)O(2)·H(2)O, the absolute configurations (1S,2S,3R,4S,5R,7S,8S,10R,13S) for the nine chiral centres of the mol­ecule has been determined. In the crystal, mol­ecules are linked by O—H⋯O and O—H⋯Cl hydrogen bonds.

Detalles Bibliográficos
Autores principales: Zhang, Chen, Xie, Cheng, Chang, Jun, Lu, Hong-Fu, Sun, Xun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051954/
https://www.ncbi.nlm.nih.gov/pubmed/21522314
http://dx.doi.org/10.1107/S1600536811002790
Descripción
Sumario:In the title compound, C(35)H(37)Cl(6)FO(14)·C(4)H(8)O(2)·H(2)O, the absolute configurations (1S,2S,3R,4S,5R,7S,8S,10R,13S) for the nine chiral centres of the mol­ecule has been determined. In the crystal, mol­ecules are linked by O—H⋯O and O—H⋯Cl hydrogen bonds.

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