5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione

The title compound, C(18)H(21)NO(3), was obtained via a double Mannich condensation reaction of 6-methyl­tetra­hydro­isobenzofuran-1,7(3H,7aH)-dione with formaldehyde and benzyl­amine. The mol­ecule contains three fused rings of which the cyclo­hexa­none and piperidine rings adopt chair conformation...

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Detalles Bibliográficos
Autores principales: Yang, Zhan-Kun, Wang, Feng-Peng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051963/
https://www.ncbi.nlm.nih.gov/pubmed/21522339
http://dx.doi.org/10.1107/S160053681100300X
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author Yang, Zhan-Kun
Wang, Feng-Peng
author_facet Yang, Zhan-Kun
Wang, Feng-Peng
author_sort Yang, Zhan-Kun
collection PubMed
description The title compound, C(18)H(21)NO(3), was obtained via a double Mannich condensation reaction of 6-methyl­tetra­hydro­isobenzofuran-1,7(3H,7aH)-dione with formaldehyde and benzyl­amine. The mol­ecule contains three fused rings of which the cyclo­hexa­none and piperidine rings adopt chair conformations and the furan­one ring assumes an envelope conformation. An inter­molecular C—H⋯π inter­action is present in the crystal structure.
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spelling pubmed-30519632011-04-26 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione Yang, Zhan-Kun Wang, Feng-Peng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(18)H(21)NO(3), was obtained via a double Mannich condensation reaction of 6-methyl­tetra­hydro­isobenzofuran-1,7(3H,7aH)-dione with formaldehyde and benzyl­amine. The mol­ecule contains three fused rings of which the cyclo­hexa­none and piperidine rings adopt chair conformations and the furan­one ring assumes an envelope conformation. An inter­molecular C—H⋯π inter­action is present in the crystal structure. International Union of Crystallography 2011-02-05 /pmc/articles/PMC3051963/ /pubmed/21522339 http://dx.doi.org/10.1107/S160053681100300X Text en © Yang and Wang 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yang, Zhan-Kun
Wang, Feng-Peng
5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title_full 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title_fullStr 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title_full_unstemmed 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title_short 5-Benzyl-7-methyl­hexa­hydro-3a,7-methano-1H-furo[3,4-c]azocine-3,10(4H)-dione
title_sort 5-benzyl-7-methyl­hexa­hydro-3a,7-methano-1h-furo[3,4-c]azocine-3,10(4h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051963/
https://www.ncbi.nlm.nih.gov/pubmed/21522339
http://dx.doi.org/10.1107/S160053681100300X
work_keys_str_mv AT yangzhankun 5benzyl7methylhexahydro3a7methano1hfuro34cazocine3104hdione
AT wangfengpeng 5benzyl7methylhexahydro3a7methano1hfuro34cazocine3104hdione

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