3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one

There are two structurally similar but crystallographically independent mol­ecules (A and B) in the asymmetric unit of the title compound, C(21)H(22)N(2)O(2), which are linked via two O—H⋯O hydrogen bonds. An intramolecular O—H⋯O hydrogen bond also occurs in each molecule. In the crystal, the A and...

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Detalles Bibliográficos
Autores principales: Wera, Michał, Pivovarenko, Vasyl G., Sikorski, Artur, Lis, Tadeusz, Błażejowski, Jerzy
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051995/
https://www.ncbi.nlm.nih.gov/pubmed/21522406
http://dx.doi.org/10.1107/S1600536811005046
Descripción
Sumario:There are two structurally similar but crystallographically independent mol­ecules (A and B) in the asymmetric unit of the title compound, C(21)H(22)N(2)O(2), which are linked via two O—H⋯O hydrogen bonds. An intramolecular O—H⋯O hydrogen bond also occurs in each molecule. In the crystal, the A and B mol­ecules are further linked through C—H⋯O inter­actions. The benzene ring is twisted at an angle of 69.9 (1) and 83.4 (1)° relative to the 1,4-dihydro­quinoline skeleton in mol­ecules A and B, respectively. Adjacent 1,4-dihydro­quinoline units of mol­ecules A are parallel, while mol­ecules A and B are oriented at an angle of 32.8 (1)°.

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