3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one

There are two structurally similar but crystallographically independent mol­ecules (A and B) in the asymmetric unit of the title compound, C(21)H(22)N(2)O(2), which are linked via two O—H⋯O hydrogen bonds. An intramolecular O—H⋯O hydrogen bond also occurs in each molecule. In the crystal, the A and...

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Autores principales: Wera, Michał, Pivovarenko, Vasyl G., Sikorski, Artur, Lis, Tadeusz, Błażejowski, Jerzy
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051995/
https://www.ncbi.nlm.nih.gov/pubmed/21522406
http://dx.doi.org/10.1107/S1600536811005046
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author Wera, Michał
Pivovarenko, Vasyl G.
Sikorski, Artur
Lis, Tadeusz
Błażejowski, Jerzy
author_facet Wera, Michał
Pivovarenko, Vasyl G.
Sikorski, Artur
Lis, Tadeusz
Błażejowski, Jerzy
author_sort Wera, Michał
collection PubMed
description There are two structurally similar but crystallographically independent mol­ecules (A and B) in the asymmetric unit of the title compound, C(21)H(22)N(2)O(2), which are linked via two O—H⋯O hydrogen bonds. An intramolecular O—H⋯O hydrogen bond also occurs in each molecule. In the crystal, the A and B mol­ecules are further linked through C—H⋯O inter­actions. The benzene ring is twisted at an angle of 69.9 (1) and 83.4 (1)° relative to the 1,4-dihydro­quinoline skeleton in mol­ecules A and B, respectively. Adjacent 1,4-dihydro­quinoline units of mol­ecules A are parallel, while mol­ecules A and B are oriented at an angle of 32.8 (1)°.
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spelling pubmed-30519952011-04-26 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one Wera, Michał Pivovarenko, Vasyl G. Sikorski, Artur Lis, Tadeusz Błażejowski, Jerzy Acta Crystallogr Sect E Struct Rep Online Organic Papers There are two structurally similar but crystallographically independent mol­ecules (A and B) in the asymmetric unit of the title compound, C(21)H(22)N(2)O(2), which are linked via two O—H⋯O hydrogen bonds. An intramolecular O—H⋯O hydrogen bond also occurs in each molecule. In the crystal, the A and B mol­ecules are further linked through C—H⋯O inter­actions. The benzene ring is twisted at an angle of 69.9 (1) and 83.4 (1)° relative to the 1,4-dihydro­quinoline skeleton in mol­ecules A and B, respectively. Adjacent 1,4-dihydro­quinoline units of mol­ecules A are parallel, while mol­ecules A and B are oriented at an angle of 32.8 (1)°. International Union of Crystallography 2011-02-19 /pmc/articles/PMC3051995/ /pubmed/21522406 http://dx.doi.org/10.1107/S1600536811005046 Text en © Wera et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wera, Michał
Pivovarenko, Vasyl G.
Sikorski, Artur
Lis, Tadeusz
Błażejowski, Jerzy
3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title_full 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title_fullStr 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title_full_unstemmed 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title_short 3-Hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1H)-one
title_sort 3-hy­droxy-1-methyl-2-[4-(piperidin-1-yl)phen­yl]quinolin-4(1h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051995/
https://www.ncbi.nlm.nih.gov/pubmed/21522406
http://dx.doi.org/10.1107/S1600536811005046
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AT sikorskiartur 3hydroxy1methyl24piperidin1ylphenylquinolin41hone
AT listadeusz 3hydroxy1methyl24piperidin1ylphenylquinolin41hone
AT błazejowskijerzy 3hydroxy1methyl24piperidin1ylphenylquinolin41hone

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