Methyl 2-(1H-indole-3-carboxamido)­acetate

The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional netwo...

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Detalles Bibliográficos
Autores principales: Hu, Fang, Zheng, Le, Zeng, Xiang Chao, Li, Kai Ping
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052031/
https://www.ncbi.nlm.nih.gov/pubmed/21522481
http://dx.doi.org/10.1107/S1600536811006660
Descripción
Sumario:The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional network by N—H⋯O hydrogen bonds involving the indole N atom. In the molecule, the indole skeleton is nearly planar [maximum deviation = 0.012 (1) Å] and the mean plane of the amido group is twisted from the mean plane of indole ring by 17.2 (1)°.

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