Methyl 2-(1H-indole-3-carboxamido)­acetate

The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional netwo...

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Detalles Bibliográficos
Autores principales: Hu, Fang, Zheng, Le, Zeng, Xiang Chao, Li, Kai Ping
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052031/
https://www.ncbi.nlm.nih.gov/pubmed/21522481
http://dx.doi.org/10.1107/S1600536811006660
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author Hu, Fang
Zheng, Le
Zeng, Xiang Chao
Li, Kai Ping
author_facet Hu, Fang
Zheng, Le
Zeng, Xiang Chao
Li, Kai Ping
author_sort Hu, Fang
collection PubMed
description The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional network by N—H⋯O hydrogen bonds involving the indole N atom. In the molecule, the indole skeleton is nearly planar [maximum deviation = 0.012 (1) Å] and the mean plane of the amido group is twisted from the mean plane of indole ring by 17.2 (1)°.
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spelling pubmed-30520312011-04-26 Methyl 2-(1H-indole-3-carboxamido)­acetate Hu, Fang Zheng, Le Zeng, Xiang Chao Li, Kai Ping Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional network by N—H⋯O hydrogen bonds involving the indole N atom. In the molecule, the indole skeleton is nearly planar [maximum deviation = 0.012 (1) Å] and the mean plane of the amido group is twisted from the mean plane of indole ring by 17.2 (1)°. International Union of Crystallography 2011-02-26 /pmc/articles/PMC3052031/ /pubmed/21522481 http://dx.doi.org/10.1107/S1600536811006660 Text en © Hu et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Hu, Fang
Zheng, Le
Zeng, Xiang Chao
Li, Kai Ping
Methyl 2-(1H-indole-3-carboxamido)­acetate
title Methyl 2-(1H-indole-3-carboxamido)­acetate
title_full Methyl 2-(1H-indole-3-carboxamido)­acetate
title_fullStr Methyl 2-(1H-indole-3-carboxamido)­acetate
title_full_unstemmed Methyl 2-(1H-indole-3-carboxamido)­acetate
title_short Methyl 2-(1H-indole-3-carboxamido)­acetate
title_sort methyl 2-(1h-indole-3-carboxamido)­acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052031/
https://www.ncbi.nlm.nih.gov/pubmed/21522481
http://dx.doi.org/10.1107/S1600536811006660
work_keys_str_mv AT hufang methyl21hindole3carboxamidoacetate
AT zhengle methyl21hindole3carboxamidoacetate
AT zengxiangchao methyl21hindole3carboxamidoacetate
AT likaiping methyl21hindole3carboxamidoacetate

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