2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone

In the title compound, C(13)H(16)ClFN(2)O, the piperazine ring is flanked by 1-(2-fluoro­benz­yl)piperazine and adopts a chair conformation. The dihedral angle between the fluoro­phenyl ring and the four planar C atoms (r.m.s. = 0.0055 Å) of the piperazine chair is 78.27 (7)°, whereas the dihedral a...

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Detalles Bibliográficos
Autores principales: Zhang, Cunlong, Zhai, Xin, Wan, Furen, Gong, Ping, Jiang, Yuyang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052134/
https://www.ncbi.nlm.nih.gov/pubmed/21522451
http://dx.doi.org/10.1107/S1600536811006180
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author Zhang, Cunlong
Zhai, Xin
Wan, Furen
Gong, Ping
Jiang, Yuyang
author_facet Zhang, Cunlong
Zhai, Xin
Wan, Furen
Gong, Ping
Jiang, Yuyang
author_sort Zhang, Cunlong
collection PubMed
description In the title compound, C(13)H(16)ClFN(2)O, the piperazine ring is flanked by 1-(2-fluoro­benz­yl)piperazine and adopts a chair conformation. The dihedral angle between the fluoro­phenyl ring and the four planar C atoms (r.m.s. = 0.0055 Å) of the piperazine chair is 78.27 (7)°, whereas the dihedral angle between the four planar C atoms of the piperazine chair and the ethanone plane is 55.21 (9) Å; the Cl atom displaced by1.589 (2) Å out of the plane.
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spelling pubmed-30521342011-04-26 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone Zhang, Cunlong Zhai, Xin Wan, Furen Gong, Ping Jiang, Yuyang Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(13)H(16)ClFN(2)O, the piperazine ring is flanked by 1-(2-fluoro­benz­yl)piperazine and adopts a chair conformation. The dihedral angle between the fluoro­phenyl ring and the four planar C atoms (r.m.s. = 0.0055 Å) of the piperazine chair is 78.27 (7)°, whereas the dihedral angle between the four planar C atoms of the piperazine chair and the ethanone plane is 55.21 (9) Å; the Cl atom displaced by1.589 (2) Å out of the plane. International Union of Crystallography 2011-02-26 /pmc/articles/PMC3052134/ /pubmed/21522451 http://dx.doi.org/10.1107/S1600536811006180 Text en © Zhang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhang, Cunlong
Zhai, Xin
Wan, Furen
Gong, Ping
Jiang, Yuyang
2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title_full 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title_fullStr 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title_full_unstemmed 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title_short 2-Chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
title_sort 2-chloro-1-[4-(2-fluoro­benz­yl)piperazin-1-yl]ethanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052134/
https://www.ncbi.nlm.nih.gov/pubmed/21522451
http://dx.doi.org/10.1107/S1600536811006180
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AT zhaixin 2chloro142fluorobenzylpiperazin1ylethanone
AT wanfuren 2chloro142fluorobenzylpiperazin1ylethanone
AT gongping 2chloro142fluorobenzylpiperazin1ylethanone
AT jiangyuyang 2chloro142fluorobenzylpiperazin1ylethanone

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