2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one

In the title compound, C(26)H(28)FN(5)O(3), the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q (T) = 0.5437 (15) Å, θ = 8.89 (15) and ϕ = 357.2 (11)°]. The 1,6-dihydro­pyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings...

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Detalles Bibliográficos
Autores principales: Aydın, Abdullah, Şüküroğlu, Murat, Akkurt, Mehmet, Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052151/
https://www.ncbi.nlm.nih.gov/pubmed/21522416
http://dx.doi.org/10.1107/S1600536811005071
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author Aydın, Abdullah
Şüküroğlu, Murat
Akkurt, Mehmet
Büyükgüngör, Orhan
author_facet Aydın, Abdullah
Şüküroğlu, Murat
Akkurt, Mehmet
Büyükgüngör, Orhan
author_sort Aydın, Abdullah
collection PubMed
description In the title compound, C(26)H(28)FN(5)O(3), the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q (T) = 0.5437 (15) Å, θ = 8.89 (15) and ϕ = 357.2 (11)°]. The 1,6-dihydro­pyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings, respectively. In the crystal, mol­ecules are linked along the c axis by C—H⋯O inter­actions and are flattened parallel to the ac plane. C–H⋯π inter­actions also contribute to the stability of the structure.
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spelling pubmed-30521512011-04-26 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one Aydın, Abdullah Şüküroğlu, Murat Akkurt, Mehmet Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(26)H(28)FN(5)O(3), the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q (T) = 0.5437 (15) Å, θ = 8.89 (15) and ϕ = 357.2 (11)°]. The 1,6-dihydro­pyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings, respectively. In the crystal, mol­ecules are linked along the c axis by C—H⋯O inter­actions and are flattened parallel to the ac plane. C–H⋯π inter­actions also contribute to the stability of the structure. International Union of Crystallography 2011-02-19 /pmc/articles/PMC3052151/ /pubmed/21522416 http://dx.doi.org/10.1107/S1600536811005071 Text en © Aydın et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Aydın, Abdullah
Şüküroğlu, Murat
Akkurt, Mehmet
Büyükgüngör, Orhan
2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title_full 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title_fullStr 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title_full_unstemmed 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title_short 2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one
title_sort 2-{2-[4-(4-fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052151/
https://www.ncbi.nlm.nih.gov/pubmed/21522416
http://dx.doi.org/10.1107/S1600536811005071
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