The Contribution of Coevolving Residues to the Stability of KDO8P Synthase

BACKGROUND: The evolutionary tree of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO8P) synthase (KDO8PS), a bacterial enzyme that catalyzes a key step in the biosynthesis of bacterial endotoxin, is evenly divided between metal and non-metal forms, both having similar structures, but diverging in vari...

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Detalles Bibliográficos
Autores principales: Ackerman, Sharon H., Gatti, Domenico L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052366/
https://www.ncbi.nlm.nih.gov/pubmed/21408011
http://dx.doi.org/10.1371/journal.pone.0017459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052366/
https://www.ncbi.nlm.nih.gov/pubmed/21408011
http://dx.doi.org/10.1371/journal.pone.0017459

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