Cargando…

Genetic predisposition to obesity leads to increased risk of type 2 diabetes

AIMS/HYPOTHESIS: Obesity is a major risk factor for type 2 diabetes. Recent genome-wide association (GWA) studies have identified multiple loci robustly associated with BMI and risk of obesity. However, information on their associations with type 2 diabetes is limited. Such information could help in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, S., Zhao, J. H., Luan, J., Langenberg, C., Luben, R. N., Khaw, K. T., Wareham, N. J., Loos, R. J. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052481/ https://www.ncbi.nlm.nih.gov/pubmed/21267540 http://dx.doi.org/10.1007/s00125-011-2044-5

Ejemplares similares

Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study
por: Li, Shengxu, et al.
Publicado: (2010)

A Latent Variable Partial Least Squares Path Modeling Approach to Regional Association and Polygenic Effect with Applications to a Human Obesity Study
por: Xue, Fuzhong, et al.
Publicado: (2012)

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
por: Lotta, Luca A., et al.
Publicado: (2016)

Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk
por: Walker, Celia G., et al.
Publicado: (2015)

Mendelian Randomization Study of B-Type Natriuretic Peptide and Type 2 Diabetes: Evidence of Causal Association from Population Studies
por: Pfister, Roman, et al.
Publicado: (2011)

Association Between Type of Dietary Fish and Seafood Intake and the Risk of Incident Type 2 Diabetes: The European Prospective Investigation of Cancer (EPIC)-Norfolk cohort study
por: Patel, Pinal S., et al.
Publicado: (2009)

Dietary Energy Density Predicts the Risk of Incident Type 2 Diabetes: The European Prospective Investigation of Cancer (EPIC)-Norfolk Study
por: Wang, Jing, et al.
Publicado: (2008)

Genetic Predisposition to Central Obesity and Risk of Type 2 Diabetes: Two Independent Cohort Studies
por: Huang, Tao, et al.
Publicado: (2015)

Seropositivity and Higher Immunoglobulin G Antibody Levels Against Cytomegalovirus Are Associated With Mortality in the Population-Based European Prospective Investigation of Cancer–Norfolk Cohort
por: Gkrania-Klotsas, Effrossyni, et al.
Publicado: (2013)

Genetic Predisposition for Type 2 Diabetes, but Not for Overweight/Obesity, Is Associated with a Restricted Adipogenesis
por: Arner, Peter, et al.
Publicado: (2011)

A Prospective Study of the Association Between Quantity and Variety of Fruit and Vegetable Intake and Incident Type 2 Diabetes
por: Cooper, Andrew J., et al.
Publicado: (2012)

Incidence of Type 2 Diabetes Using Proposed HbA(1c) Diagnostic Criteria in the European Prospective Investigation of Cancer–Norfolk Cohort: Implications for preventive strategies
por: Chamnan, Parinya, et al.
Publicado: (2011)

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus
por: van Zuydam, Natalie R., et al.
Publicado: (2020)

Daytime napping, sleep duration and increased 8-year risk of type 2 diabetes in a British population
por: Leng, Y., et al.
Publicado: (2016)

Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary
por: O’Connor, Laura M., et al.
Publicado: (2014)

Estimating the potential population impact of stepwise screening strategies for identifying and treating individuals at high risk of Type 2 diabetes: a modelling study
por: Chamnan, P, et al.
Publicado: (2012)

Genetic predisposition to human lung cancer.
por: Heighway, J., et al.
Publicado: (1986)

Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries
por: Li, Sherly X., et al.
Publicado: (2018)

Genetic Markers of Adult Obesity Risk Are Associated with Greater Early Infancy Weight Gain and Growth
por: Elks, Cathy E., et al.
Publicado: (2010)

Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study
por: Kilpeläinen, Tuomas O., et al.
Publicado: (2009)

The associations of longitudinal changes in consumption of total and types of dairy products and markers of metabolic risk and adiposity: findings from the European Investigation into Cancer and Nutrition (EPIC)–Norfolk study, United Kingdom
por: Trichia, Eirini, et al.
Publicado: (2020)

Serum 25-hydroxyvitamin D, mortality, and incident cardiovascular disease, respiratory disease, cancers, and fractures: a 13-y prospective population study(1)(2)(3)(4)
por: Khaw, Kay-Tee, et al.
Publicado: (2014)

Genetic Predisposition to Dyslipidemia and Type 2 Diabetes Risk in Two Prospective Cohorts
por: Qi, Qibin, et al.
Publicado: (2012)

Combined effect of health behaviours and risk of first ever stroke in 20 040 men and women over 11 years’ follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): prospective population study
por: Myint, Phyo K, et al.
Publicado: (2009)

Longitudinal Association of C-Reactive Protein and Lung Function Over 13 Years: The EPIC-Norfolk Study
por: Ahmadi-Abhari, Sara, et al.
Publicado: (2014)

Longitudinal association of C-reactive protein and Haemoglobin A(1c) over 13 years: the European Prospective Investigation into Cancer - Norfolk study
por: Ahmadi-Abhari, Sara, et al.
Publicado: (2015)

Changes in waist circumference and risk of all-cause and CVD mortality: results from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study
por: Mulligan, Angela A., et al.
Publicado: (2019)

Mendelian Randomisation Study of Childhood BMI and Early Menarche
por: Mumby, Hannah S., et al.
Publicado: (2011)

Predicting admissions and time spent in hospital over a decade in a population-based record linkage study: the EPIC-Norfolk cohort
por: Luben, Robert, et al.
Publicado: (2016)

Debrisoquine metabolism and genetic predisposition to lung cancer.
por: Law, M. R., et al.
Publicado: (1989)

The association of the mitochondrial DNA OriB variant (16184–16193 polycytosine tract) with type 2 diabetes in Europid populations
por: Ye, Zheng, et al.
Publicado: (2013)

Caffeine intake reduces sedentary time and increases physical activity predisposition in obese police officers
por: Ferreira, G.A., et al.
Publicado: (2021)

Diabetes Genetic Predisposition Score and Cardiovascular Complications Among Patients With Type 2 Diabetes
por: Qi, Qibin, et al.
Publicado: (2013)

Distribution of lipid parameters according to different socio-economic indicators- the EPIC-Norfolk prospective population study
por: Shohaimi, Shamarina, et al.
Publicado: (2014)

Plasma Vitamin C Levels: Risk Factors for Deficiency and Association with Self-Reported Functional Health in the European Prospective Investigation into Cancer-Norfolk
por: McCall, Stephen J., et al.
Publicado: (2019)

The association between Mediterranean Diet Score and glucokinase regulatory protein gene variation on the markers of cardiometabolic risk: an analysis in the European Prospective Investigation into Cancer (EPIC)-Norfolk study
por: Sotos-Prieto, Mercedes, et al.
Publicado: (2014)

Genetic predisposition to lung cancer.
por: Law, M. R.
Publicado: (1990)

Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat
por: Walker, Celia G., et al.
Publicado: (2012)

Epigenetics and type II diabetes mellitus: underlying mechanisms of prenatal predisposition
por: Sterns, J. David, et al.
Publicado: (2014)

Narrowing down the role of common variants in the genetic predisposition to obesity
por: Calton, Melissa A, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_9pefc0n7422e0o4bjtqsoqjeqv