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Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus
The ‘classical’ swine H1N1 influenza A virus lineage was established after the devastating 1918 human pandemic virus entered domestic pig herds. A descendent of this lineage recently re-emerged in humans as the 2009 pandemic H1N1 virus. Adaptation in pigs has led to several changes in the multifunct...
Autores principales: | Hale, Benjamin G., Steel, John, Manicassamy, Balaji, Medina, Rafael A., Ye, Jianqiang, Hickman, Danielle, Lowen, Anice C., Perez, Daniel R., García-Sastre, Adolfo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052525/ https://www.ncbi.nlm.nih.gov/pubmed/20237225 http://dx.doi.org/10.1099/vir.0.020925-0 |
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