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Dendritic cells are susceptible to infection with wild-type adenovirus, inducing a differentiation arrest in precursor cells and inducing a strong T-cell stimulation
Adenovirus infection after stem cell transplantation is a significant cause of morbidity and mortality, especially in children. A robust T-cell response induced by dendritic cells (DC) is crucial for clearing the virus, suggesting their pivotal role for the response to human adenoviruses (HAdV). Des...
Autores principales: | Keßler, Tobias, Hamprecht, Klaus, Feuchtinger, Tobias, Jahn, Gerhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052561/ https://www.ncbi.nlm.nih.gov/pubmed/20032205 http://dx.doi.org/10.1099/vir.0.013920-0 |
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