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Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus

The aim of this work was to verify the effects of water soluble fraction (WSF) of diesel fuel in liver of Channa punctatus. The fishes were exposed to sublethal concentration of WSF of diesel (5%-DF1, 10%-DF2, 15%-DF3, 20%-DF4 and 25%-DF5) for 21 days. Significant histopathological lesions observed...

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Detalles Bibliográficos
Autores principales: Kakkar, Preeti Handa, Saxena, R. M., Rathee, N. S., Joshi, Mamta
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052576/
https://www.ncbi.nlm.nih.gov/pubmed/21430914
http://dx.doi.org/10.4103/0971-6580.75846
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author Kakkar, Preeti Handa
Saxena, R. M.
Rathee, N. S.
Joshi, Mamta
author_facet Kakkar, Preeti Handa
Saxena, R. M.
Rathee, N. S.
Joshi, Mamta
author_sort Kakkar, Preeti Handa
collection PubMed
description The aim of this work was to verify the effects of water soluble fraction (WSF) of diesel fuel in liver of Channa punctatus. The fishes were exposed to sublethal concentration of WSF of diesel (5%-DF1, 10%-DF2, 15%-DF3, 20%-DF4 and 25%-DF5) for 21 days. Significant histopathological lesions observed were dilation, congestion, thrombosis formation in hepatoportal blood vessel, melanomacrophage centers, hemolysis, hemorrhage, lymphocytic infiltration between the hepatocytes and necrosis & fibrosis in hepatocytes were the prominent changes in liver. The histological analysis showed increasing damages dose-dependents and time-dependents.
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spelling pubmed-30525762011-03-22 Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus Kakkar, Preeti Handa Saxena, R. M. Rathee, N. S. Joshi, Mamta Toxicol Int Original Article The aim of this work was to verify the effects of water soluble fraction (WSF) of diesel fuel in liver of Channa punctatus. The fishes were exposed to sublethal concentration of WSF of diesel (5%-DF1, 10%-DF2, 15%-DF3, 20%-DF4 and 25%-DF5) for 21 days. Significant histopathological lesions observed were dilation, congestion, thrombosis formation in hepatoportal blood vessel, melanomacrophage centers, hemolysis, hemorrhage, lymphocytic infiltration between the hepatocytes and necrosis & fibrosis in hepatocytes were the prominent changes in liver. The histological analysis showed increasing damages dose-dependents and time-dependents. Medknow Publications 2011 /pmc/articles/PMC3052576/ /pubmed/21430914 http://dx.doi.org/10.4103/0971-6580.75846 Text en © Toxicology International http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kakkar, Preeti Handa
Saxena, R. M.
Rathee, N. S.
Joshi, Mamta
Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title_full Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title_fullStr Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title_full_unstemmed Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title_short Water Soluble Fraction of Diesel Fuel Induced Histopathological Alterations in the Liver of Channa punctatus
title_sort water soluble fraction of diesel fuel induced histopathological alterations in the liver of channa punctatus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052576/
https://www.ncbi.nlm.nih.gov/pubmed/21430914
http://dx.doi.org/10.4103/0971-6580.75846
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