Cargando…

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

Chronic wasting disease (CWD) is a prion disease that affects free-ranging and captive cervids, including mule deer, white-tailed deer, Rocky Mountain elk and moose. CWD-infected cervids have been reported in 14 USA states, two Canadian provinces and in South Korea. The possibility of a zoonotic tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sandberg, Malin K., Al-Doujaily, Huda, Sigurdson, Christina J., Glatzel, Markus, O'Malley, Catherine, Powell, Caroline, Asante, Emmanuel A., Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Formato:	Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2010
Materias:	Other Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052602/ https://www.ncbi.nlm.nih.gov/pubmed/20610667 http://dx.doi.org/10.1099/vir.0.024380-0

Ejemplares similares

Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy
por: Jackson, Graham S., et al.
Publicado: (2022)

Humanized Transgenic Mice Are Resistant to Chronic Wasting Disease Prions From Norwegian Reindeer and Moose( )
por: Wadsworth, Jonathan D F, et al.
Publicado: (2021)

Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein
por: Wadsworth, Jonathan D.F., et al.
Publicado: (2013)

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked
por: Sandberg, Malin K., et al.
Publicado: (2014)

Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein
por: Asante, Emmanuel A., et al.
Publicado: (2013)

A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay
por: Edgeworth, Julie Ann, et al.
Publicado: (2011)

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins
por: Asante, Emmanuel A., et al.
Publicado: (2009)

Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein
por: Joiner, Susan, et al.
Publicado: (2018)

The origin of the prion agent of kuru: molecular and biological strain typing
por: Wadsworth, Jonathan D.F., et al.
Publicado: (2008)

Highly infectious prions are not directly neurotoxic
por: Benilova, Iryna, et al.
Publicado: (2020)

Review: Contribution of transgenic models to understanding human prion disease
por: Wadsworth, J D F, et al.
Publicado: (2010)

A naturally occurring variant of the human prion protein completely prevents prion disease
por: Asante, Emmanuel A., et al.
Publicado: (2015)

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS
por: Asante, Emmanuel A., et al.
Publicado: (2020)

Filamentous white matter prion protein deposition is a distinctive feature of multiple inherited prion diseases
por: Reiniger, Lilla, et al.
Publicado: (2013)

A systematic investigation of production of synthetic prions from recombinant prion protein
por: Schmidt, Christian, et al.
Publicado: (2015)

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS
por: Asante, Emmanuel A., et al.
Publicado: (2015)

Tau, prions and Aβ: the triad of neurodegeneration
por: Reiniger, Lilla, et al.
Publicado: (2010)

N-terminal Domain of Prion Protein Directs Its Oligomeric Association
por: Trevitt, Clare R., et al.
Publicado: (2014)

Central and peripheral pathology of kuru: pathological analysis of a recent case and comparison with other forms of human prion disease
por: Brandner, Sebastian, et al.
Publicado: (2008)

Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection
por: Castro-Seoane, Rocio, et al.
Publicado: (2012)

Lack of TAR-DNA binding protein-43 (TDP-43) pathology in human prion diseases
por: Isaacs, A M, et al.
Publicado: (2008)

Molecular pathology of human prion disease
por: Wadsworth, Jonathan D. F., et al.
Publicado: (2010)

Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin–proteasome system
por: McKinnon, Chris, et al.
Publicado: (2015)

A novel and rapid method for obtaining high titre intact prion strains from mammalian brain
por: Wenborn, Adam, et al.
Publicado: (2015)

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity
por: Nicoll, Andrew J., et al.
Publicado: (2013)

Sympathetic Prions
por: Glatzel, Markus, et al.
Publicado: (2001)

Identification of clinical target areas in the brainstem of prion‐infected mice
por: Mirabile, Ilaria, et al.
Publicado: (2015)

Abnormal prion protein, infectivity and neurofilament light-chain in blood of macaques with experimental variant Creutzfeldt-Jakob disease
por: Yakovleva, Oksana, et al.
Publicado: (2022)

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein
por: Race, Brent, et al.
Publicado: (2022)

Sex Effects in Mouse Prion Disease Incubation Time
por: Akhtar, Shaheen, et al.
Publicado: (2011)

Prion strains viewed through the lens of cryo-EM
por: Manka, Szymon W., et al.
Publicado: (2022)

Genetics of prion diseases
por: Lloyd, Sarah E, et al.
Publicado: (2013)

Phenotypic heterogeneity and genetic modification of P102L inherited prion disease in an international series
por: Webb, T. E. F., et al.
Publicado: (2008)

A structural basis for prion strain diversity
por: Manka, Szymon W., et al.
Publicado: (2023)

Ex vivo mammalian prions are formed of paired double helical prion protein fibrils
por: Terry, Cassandra, et al.
Publicado: (2016)

Transmission of Atypical Bovine Prions to Mice Transgenic for Human Prion Protein
por: Béringue, Vincent, et al.
Publicado: (2008)

Susceptibility of Human Prion Protein to Conversion by Chronic Wasting Disease Prions
por: Barria, Marcelo A., et al.
Publicado: (2018)

Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease
por: Rudge, Peter, et al.
Publicado: (2019)

Evaluating the causality of novel sequence variants in the prion protein gene by example
por: Mok, Tze How, et al.
Publicado: (2018)

Microglial Cx3cr1 knockout reduces prion disease incubation time in mice
por: Grizenkova, Julia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6pppof31844phetl59fr929921