Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

Mutations that occurred during adaptation of human cytomegalovirus to cell culture were monitored by isolating four strains from clinical samples, passaging them in various cell types and sequencing ten complete virus genomes from the final passages. Mutational dynamics were assessed by targeted seq...

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Detalles Bibliográficos
Autores principales: Dargan, Derrick J., Douglas, Elaine, Cunningham, Charles, Jamieson, Fiona, Stanton, Richard J., Baluchova, Katarina, McSharry, Brian P., Tomasec, Peter, Emery, Vincent C., Percivalle, Elena, Sarasini, Antonella, Gerna, Giuseppe, Wilkinson, Gavin W. G., Davison, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2010
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052722/
https://www.ncbi.nlm.nih.gov/pubmed/20479471
http://dx.doi.org/10.1099/vir.0.018994-0

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