Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect

The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily on more efficient energy production through mi...

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Detalles Bibliográficos
Autores principales: Shlomi, Tomer, Benyamini, Tomer, Gottlieb, Eyal, Sharan, Roded, Ruppin, Eytan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053319/
https://www.ncbi.nlm.nih.gov/pubmed/21423717
http://dx.doi.org/10.1371/journal.pcbi.1002018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053319/
https://www.ncbi.nlm.nih.gov/pubmed/21423717
http://dx.doi.org/10.1371/journal.pcbi.1002018

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