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HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct traffick...

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Detalles Bibliográficos
Autores principales: Ocwieja, Karen E., Brady, Troy L., Ronen, Keshet, Huegel, Alyssa, Roth, Shoshannah L., Schaller, Torsten, James, Leo C., Towers, Greg J., Young, John A. T., Chanda, Sumit K., König, Renate, Malani, Nirav, Berry, Charles C., Bushman, Frederic D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053352/
https://www.ncbi.nlm.nih.gov/pubmed/21423673
http://dx.doi.org/10.1371/journal.ppat.1001313

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