TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice

TDP-43 and α-synuclein are two disease proteins involved in a wide range of neurodegenerative diseases. While TDP-43 proteinopathy is considered a pathologic hallmark of sporadic amyotrophic lateral sclerosis and frontotemporal lobe degeneration, α-synuclein is a major component of Lewy body charact...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Huang, Cao, Tong, Jianbin, Yang, Ming, Zhou, Hongxia, Xia, Xu-Gang
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053535/
https://www.ncbi.nlm.nih.gov/pubmed/21448284

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