Kinetics of isoniazid transfer into cerebrospinal fluid in patients with tuberculous meningitis.

For the pharmacokinetic analysis of isoniazid transfer into CSF, steady-state isoniazid concentrations of plasma and CSF were measured in eleven tuberculous meningitis patients confirmed with findings of CSF and neuroimazing. Peak plasma levels (4.17-21.5 micrograms/mL) were achieved at 0.25 to 3 ho...

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Detalles Bibliográficos
Autores principales: Shin, S. G., Roh, J. K., Lee, N. S., Shin, J. G., Jang, I. J., Park, C. W., Myung, H. J.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053720/
https://www.ncbi.nlm.nih.gov/pubmed/2206465

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