Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. II. Kinetic properties of AP DNA endonucleases in rat liver chromatin.

An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about optimal activities of AP DNA endonucleases and N-ethylma...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Y. S., Kim, J. W., Lee, S. E., Oh, S. H.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053764/
https://www.ncbi.nlm.nih.gov/pubmed/1710900

Ejemplares similares

Ejemplares similares