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Anti-IL-4 antibody inhibits antigen specific IgE response but fails to prevent chicken gamma globulin-induced active systemic anaphylaxis: evidence for the involvement of IgG antibodies.

It has recently been reported that interleukin-4 (IL-4) is required for the production of IgE, and anti-IL-4 monoclonal antibody (mAb) inhibits in vivo IgE responses. These suggest that blocking of IL-4 activity may be useful for the prevention or treatment of immediate hypersensitivity disorders. I...

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Detalles Bibliográficos
Autores principales: Lee, H. K., Lee, H. H., Park, Y. M., Park, H. J., Lee, J. H., Ha, T. Y.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053941/
https://www.ncbi.nlm.nih.gov/pubmed/8835757