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Isoniazid resistance and the point mutation of codon 463 of katG gene of Mycobacterium tuberculosis.
It has long been known that almost all isoniazid (INH) resistant mycobacteria lose the catalase and peroxidase activities along with reduced or no virulence for guinea pigs. Recently resistance to INH has become known to be associated with mutations of katG gene encoding the HPI (Hydroperoxidase I)...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Korean Academy of Medical Sciences
1997
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054244/ https://www.ncbi.nlm.nih.gov/pubmed/9170012 |