Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.

While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of...

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Detalles Bibliográficos
Autores principales: Kwon, S. Y., Lee, J. J., Chung, I. J., Kim, H. J., Park, M. R., Kim, H. S., Park, C. S.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054438/
https://www.ncbi.nlm.nih.gov/pubmed/10642947
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author Kwon, S. Y.
Lee, J. J.
Chung, I. J.
Kim, H. J.
Park, M. R.
Kim, H. S.
Park, C. S.
author_facet Kwon, S. Y.
Lee, J. J.
Chung, I. J.
Kim, H. J.
Park, M. R.
Kim, H. S.
Park, C. S.
author_sort Kwon, S. Y.
collection PubMed
description While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of unknown origin. An abdominal CT scan revealed splenomegaly with focal splenic infarction. Splenectomy and a liver wedge biopsy showed sinusoidal-pattern infiltration of medium to large tumor cells with positive reaction to a B-lymphocyte marker. Findings on bone marrow examination showed proliferation of histiocytes with avid hemophagocytosis.
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spelling pubmed-30544382011-03-15 Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report. Kwon, S. Y. Lee, J. J. Chung, I. J. Kim, H. J. Park, M. R. Kim, H. S. Park, C. S. J Korean Med Sci Research Article While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of unknown origin. An abdominal CT scan revealed splenomegaly with focal splenic infarction. Splenectomy and a liver wedge biopsy showed sinusoidal-pattern infiltration of medium to large tumor cells with positive reaction to a B-lymphocyte marker. Findings on bone marrow examination showed proliferation of histiocytes with avid hemophagocytosis. Korean Academy of Medical Sciences 1999-12 /pmc/articles/PMC3054438/ /pubmed/10642947 Text en
spellingShingle Research Article
Kwon, S. Y.
Lee, J. J.
Chung, I. J.
Kim, H. J.
Park, M. R.
Kim, H. S.
Park, C. S.
Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title_full Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title_fullStr Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title_full_unstemmed Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title_short Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.
title_sort hepatosplenic b-cell lymphoma associated with hemophagocytic syndrome: a case report.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054438/
https://www.ncbi.nlm.nih.gov/pubmed/10642947
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