Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.

We report a 27-year-old woman who developed Coombs' negative hemolytic anemia and fulminant hepatic failure as the initial manifestation of Wilson's disease. Unmeasurably low level of serum alkaline phosphatase provided a clue to the diagnosis of Wilson's disease. The diagnosis was es...

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Detalles Bibliográficos
Autores principales: Lee, J. J., Kim, H. J., Chung, I. J., Kook, H., Byun, J. R., Kwon, S. Y., Park, M. R., Choi, K. S., Hwang, T. J., Ryang, D. W.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054522/
https://www.ncbi.nlm.nih.gov/pubmed/9811188
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author Lee, J. J.
Kim, H. J.
Chung, I. J.
Kook, H.
Byun, J. R.
Kwon, S. Y.
Park, M. R.
Choi, K. S.
Hwang, T. J.
Ryang, D. W.
author_facet Lee, J. J.
Kim, H. J.
Chung, I. J.
Kook, H.
Byun, J. R.
Kwon, S. Y.
Park, M. R.
Choi, K. S.
Hwang, T. J.
Ryang, D. W.
author_sort Lee, J. J.
collection PubMed
description We report a 27-year-old woman who developed Coombs' negative hemolytic anemia and fulminant hepatic failure as the initial manifestation of Wilson's disease. Unmeasurably low level of serum alkaline phosphatase provided a clue to the diagnosis of Wilson's disease. The diagnosis was established with the presence of Kayser-Fleischer ring, decreased serum ceruloplasmin level, and elevated urine and serum copper levels. In spite of repeated plasmapheresis, she died of multiorgan failure on the fifth hospital day.
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spelling pubmed-30545222011-03-15 Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report. Lee, J. J. Kim, H. J. Chung, I. J. Kook, H. Byun, J. R. Kwon, S. Y. Park, M. R. Choi, K. S. Hwang, T. J. Ryang, D. W. J Korean Med Sci Research Article We report a 27-year-old woman who developed Coombs' negative hemolytic anemia and fulminant hepatic failure as the initial manifestation of Wilson's disease. Unmeasurably low level of serum alkaline phosphatase provided a clue to the diagnosis of Wilson's disease. The diagnosis was established with the presence of Kayser-Fleischer ring, decreased serum ceruloplasmin level, and elevated urine and serum copper levels. In spite of repeated plasmapheresis, she died of multiorgan failure on the fifth hospital day. Korean Academy of Medical Sciences 1998-10 /pmc/articles/PMC3054522/ /pubmed/9811188 Text en
spellingShingle Research Article
Lee, J. J.
Kim, H. J.
Chung, I. J.
Kook, H.
Byun, J. R.
Kwon, S. Y.
Park, M. R.
Choi, K. S.
Hwang, T. J.
Ryang, D. W.
Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title_full Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title_fullStr Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title_full_unstemmed Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title_short Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.
title_sort acute hemolytic crisis with fulminant hepatic failure as the first manifestation of wilson's disease: a case report.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054522/
https://www.ncbi.nlm.nih.gov/pubmed/9811188
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