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Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome.

One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the incidence and role of MDR1 gene expression in patients with acute leukemia, we investigated the e...

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Detalles Bibliográficos
Autores principales:	Jiang, E. Z., Chang, Y. J., Lee, J. W., Lee, W. K., Kim, J. S., Sohn, S. K., Lee, K. B., Suh, J. S.
Formato:	Texto
Lenguaje:	English
Publicado:	Korean Academy of Medical Sciences 1998
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054545/ https://www.ncbi.nlm.nih.gov/pubmed/9886170

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