Cargando…

Potentials and limitations of adenovirus-p53 gene therapy for brain tumors.

We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and U-87 and EFC-2 expressing wild-type p53) and two rat glioma cell lines (9L and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Y. K., Joe, Y. A., Yang, Y. J., Lee, K. S., Son, B. C., Jeun, S. S., Chung, D. S., Cho, K. K., Park, C. K., Kim, M. C., Kim, H. K., Yung, W. K., Kang, J. K.
Formato:	Texto
Lenguaje:	English
Publicado:	Korean Academy of Medical Sciences 2000
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054646/ https://www.ncbi.nlm.nih.gov/pubmed/10895975

Ejemplares similares

Silencing E1A mRNA by RNA interference inhibits adenovirus replication
por: Chung, Y.-S., et al.
Publicado: (2007)

p53 mutation and epidermal growth factor receptor overexpression in glioblastoma.
por: Yoon, K. S., et al.
Publicado: (2001)

The relationship between microvessel count and the expression of vascular endothelial growth factor, p53, and K-ras in non-small cell lung cancer.
por: Kang, Y. H., et al.
Publicado: (2001)

Role of p53 gene mutation in tumor aggressiveness of intracranial meningiomas.
por: Cho, H., et al.
Publicado: (1999)

Loss of heterozygosity on chromosome 10, 13q(Rb), 17p, and p53 gene mutations in human brain gliomas.
por: Lee, S. H., et al.
Publicado: (1995)

Inhibition of breast cancer growth in vivo by antiangiogenesis gene therapy with adenovirus-mediated antisense-VEGF
por: Im, S-A, et al.
Publicado: (2001)

Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
por: Leung, W K, et al.
Publicado: (2001)

Preliminary experiences with intraoperative radiation therapy (IORT) for the treatment of brain tumors.
por: Chung, Y. G., et al.
Publicado: (1995)

Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53
por: Park, E K, et al.
Publicado: (2015)

The effect of isochromosome 17q presence, proliferative and apoptotic indices, expression of c-erbB-2, bcl-2 and p53 proteins on the prognosis of medulloblastoma.
por: Nam, D. H., et al.
Publicado: (2000)

Comparison of p53 gene mutations in paired primary and metastatic gastric tumor tissues.
por: Kim, J. H., et al.
Publicado: (1993)

Human papillomavirus 16/18 expression of endocervical glandular lesions: relationship with p53 and MIB-1 Expressions.
por: Yoon, H. K., et al.
Publicado: (2001)

Topographic expression of p21WAF1/SDI1/CIP1, bcl2, and p53 is altered at the early stage of colorectal carcinogenesis.
por: Cho, J. H., et al.
Publicado: (2000)

The expression of p73 is increased in lung cancer, independent of p53 gene alteration
por: Tokuchi, Y, et al.
Publicado: (1999)

High isolation rate of adenovirus serotype 7 from South Korean military recruits with mild acute respiratory disease
por: Jeon, K, et al.
Publicado: (2007)

An immunohistochemical study of the expression of p53 protein in colon cancer.
por: Kim, Y. W., et al.
Publicado: (1995)

Adenovirus-mediated p53 tumor suppressor gene therapy against subcutaneous HuH7 hepatoma cell line nodule of nude mice.
por: Choi, J. Y., et al.
Publicado: (1999)

The effects of mesenchymal stem cells injected via different routes on modified IL-12-mediated antitumor activity
por: Seo, S H, et al.
Publicado: (2011)

Immunohistochemical detection of p53 protein, c-erbB-2 protein, epidermal growth factor receptor protein and proliferating cell nuclear antigen in gastric carcinoma.
por: Jang, W. I., et al.
Publicado: (1993)

ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells
por: Ci, Y, et al.
Publicado: (2014)

Deletions of 9p21 and TP53 in bladder cancer.
por: Park, W. S., et al.
Publicado: (1996)

MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death
por: Oka, S, et al.
Publicado: (2014)

MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death
por: Oka, S, et al.
Publicado: (2015)

Resequencing microarray for detection of human adenoviruses in patients with conjunctivitis
por: Woo, Patrick C.Y., et al.
Publicado: (2010)

PB1913: SYNERGISTIC EFFECTS OF DECITABINE AND APR-246 IN TP53 P.248Q-MUTATED MYELODYSPLASTIC SYNDROME
por: Fang, Y., et al.
Publicado: (2022)

Increased serum levels of mutant p53 proteins in patients with colorectal cancer.
por: Shim, K. S., et al.
Publicado: (1998)

Simultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci
por: Frosi, Y., et al.
Publicado: (2019)

Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy
por: Kang, J H, et al.
Publicado: (2016)

WTH3 is a direct target of the p53 protein
por: Tian, K, et al.
Publicado: (2007)

Growth Performance and Carcass Characteristics of Korean Native Ducks Fed Diets with Varying Levels of Limiting Amino Acids
por: Choo, Y. K., et al.
Publicado: (2014)

Expression of p53 protein, PCNA, and Ki-67 in osteosarcomas of bone.
por: Park, H. R., et al.
Publicado: (1995)

A Novel Psittacine Adenovirus Identified During an Outbreak of Avian Chlamydiosis and Human Psittacosis: Zoonosis Associated with Virus-Bacterium Coinfection in Birds
por: To, Kelvin K. W., et al.
Publicado: (2014)

Immunohistochemical analysis of p53 protein expression in benign and malignant skin tumors using a panel of anti-p53 antibodies.
por: Ro, Y. S., et al.
Publicado: (1993)

Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus
por: Wong, Samson S. Y., et al.
Publicado: (2018)

p53 mutations and human papillomavirus DNA in oral squamous cell carcinoma: correlation with apoptosis.
por: Koh, J. Y., et al.
Publicado: (1998)

Brain tumor in the first year of life: a single institute study.
por: Chung, S. K., et al.
Publicado: (1998)

Over-expression of p53 protein in squamous cell carcinoma of the skin.
por: Rhim, K. J., et al.
Publicado: (1995)

A tumour-associated cell-surface glycoprotein accompanying p53 overexpression and higher growth potential for gastric cancer.
por: Maehara, Y., et al.
Publicado: (1995)

Have a novel guideline of American Heart Association outlived usefulness in early differentiated diagnosis of acute aortic dissection
por: Park, C, et al.
Publicado: (2013)

Comparison of basophil histamine releasability between atopic and nonatopic asthmatics.
por: Son, J. W., et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_sac7q5hpavr05qan8201kbjluh