Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.

Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach m...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwak, H. S., Sohn, M. H., Lim, S. T., Kwak, J. Y., Yim, C. Y.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054685/
https://www.ncbi.nlm.nih.gov/pubmed/11069001
_version_ 1782200005724995584
author Kwak, H. S.
Sohn, M. H.
Lim, S. T.
Kwak, J. Y.
Yim, C. Y.
author_facet Kwak, H. S.
Sohn, M. H.
Lim, S. T.
Kwak, J. Y.
Yim, C. Y.
author_sort Kwak, H. S.
collection PubMed
description Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach may occur. Our two cases were admitted because of severe hypercalcemia in accelerated phase of CML. On Tc-99m methylene diphosphonate (MDP) bone scintigraphies, a marked tracer accumulation was seen in the lung, heart, stomach and kidney. We report increased tracer accumulation of multiple organs on Tc-99m MDP bone scintigraphy in two rare hypercalcemic patients with CML.
format Text
id pubmed-3054685
institution National Center for Biotechnology Information
language English
publishDate 2000
publisher Korean Academy of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-30546852011-03-15 Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia. Kwak, H. S. Sohn, M. H. Lim, S. T. Kwak, J. Y. Yim, C. Y. J Korean Med Sci Research Article Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach may occur. Our two cases were admitted because of severe hypercalcemia in accelerated phase of CML. On Tc-99m methylene diphosphonate (MDP) bone scintigraphies, a marked tracer accumulation was seen in the lung, heart, stomach and kidney. We report increased tracer accumulation of multiple organs on Tc-99m MDP bone scintigraphy in two rare hypercalcemic patients with CML. Korean Academy of Medical Sciences 2000-10 /pmc/articles/PMC3054685/ /pubmed/11069001 Text en
spellingShingle Research Article
Kwak, H. S.
Sohn, M. H.
Lim, S. T.
Kwak, J. Y.
Yim, C. Y.
Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title_full Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title_fullStr Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title_full_unstemmed Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title_short Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
title_sort technetium-99m mdp bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054685/
https://www.ncbi.nlm.nih.gov/pubmed/11069001
work_keys_str_mv AT kwakhs technetium99mmdpbonescintigraphicfindingsofhypercalcemiainacceleratedphaseofchronicmyelogenousleukemia
AT sohnmh technetium99mmdpbonescintigraphicfindingsofhypercalcemiainacceleratedphaseofchronicmyelogenousleukemia
AT limst technetium99mmdpbonescintigraphicfindingsofhypercalcemiainacceleratedphaseofchronicmyelogenousleukemia
AT kwakjy technetium99mmdpbonescintigraphicfindingsofhypercalcemiainacceleratedphaseofchronicmyelogenousleukemia
AT yimcy technetium99mmdpbonescintigraphicfindingsofhypercalcemiainacceleratedphaseofchronicmyelogenousleukemia

Ejemplares similares