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Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells.
Interleukin 1beta(IL-1beta), a proinflammatory cytokine, is related with inflammatory diseases and it up-regulates MUC2 gene expression and mucin secretion. This study was designed to investigate the signal transduction pathway of the IL-1beta-mediated MUC2 gene expression and mucin secretion in hum...
Autores principales: | Kim, Yong-Dae, Jeon, Jae-Yun, Woo, Hyun Jae, Lee, Jung Cheul, Chung, Jin Hong, Song, Si Youn, Yoon, Seok-Keun, Baek, Suk-Hwan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Korean Academy of Medical Sciences
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054965/ https://www.ncbi.nlm.nih.gov/pubmed/12482999 |
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